Pediatric Eye Disease Investigator Group (PEDIG)

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Manuscripts

General

1. Wallace DK, Lazar EL, Melia M, Birch EE, Holmes JM, Hopkins KB, Kraker RT, Kulp MT, Pang Y, Repka MX, Tamkins SM, Weise KK, on behalf of the Pediatric Eye Disease Investigator Group. Stereoacuity in Children with Anisometropic Amblyopia. J AAPOS 2011;15(5):455-61. (Published).
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2. Holmes JM, Lazar EL, Melia BM, Astle WF, Dagi LR, Donahue SP, Frazier MG, Hertle RW, Repka MX, Quinn GE, Weise KK, for the Pediatric Eye Disease Investigator Group. Effect of Age on Response to Amblyopia Treatment in Children. Arch Ophthalmol. 2011;129(11):1451-7. Epub 2011 Jul 11. (Published).
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3. Frick KD, Hariharan L, Repka MX, Chandler D, Melia BM, Beck RW, for the Pediatric Eye Disease Investigator Group. Cost-effectiveness of 2 Approaches to Managing Nasolacrimal Duct Obstruction in Infants: The Importance of the Spontaneous Resolution Rate. Arch Ophthalmol. 2011; 129(5):603-9. (Published).
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4. Repka MX, Simons K, Kraker R, Pediatric Eye Disease Investigator Group. Laterality of amblyopia. Am J Ophthalmol. 2010;150(2):270-4. (Published).
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5. Birch EE, Strauber SF, Beck RW, et al. Comparison of the Amblyopia Treatment Study HOTV and Electronic-Early Treatment of Diabetic Retinopathy Study visual acuity protocols in amblyopic children aged 5 to 11 years. J AAPOS 2009;13(1):75-8 (Published).
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6. Holmes JM, Strauber SF, Quinn GE, et al. Further validation of the Amblyopia Treatment Index parental questionnaire. J AAPOS 2008;12(6):581-4 (Published).
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7. Holmes JM, Birch EE, Leske DA, Fu VL, Mohney BG.. New tests of distance stereoacuity and their role in evaluating intermittent exotropia.. Ophthalmology. 2007 Jun;114(6):1215-20. (Published).
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8. Leske DA, Birch EE, Holmes JM. Real depth vs randot stereotests. Am J Ophthalmol 2006;142(4):699-701 (Published).
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9. Holmes JM, Leske DA, Cole SR, et al. A symptom survey and quality of life questionnaire for nasolacrimal duct obstruction in children. Ophthalmology 2006;113(9):1675-80 (Published).
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10. Mohney BG, Holmes JM. An office-based scale for assessing control in intermittent exotropia. Strabismus 2006;14(3):147-50 (Published).
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11. Holmes JM, Clarke MP. Amblyopia. Lancet 2006; 367:1343-51. (Published).
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12. Holmes JM, Repka MX, Kraker RT, Clarke MP. The treatment of amblyopia. Strabismus 2006;14(1):37-42 (Published).
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13. Rice ML, Birch E, Holmes JM. An abbreviated reading speed test. Optom Vis Sci 2005;82(2):128-33 (Published).
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14. Holmes JM, Fawcett SL. Testing distance stereoacuity with the Frisby-Davis 2 (FD2) test. Am J Ophthalmol 2005;139(1):193-5 (Published).
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15. Quinn GE, Beck RW, Holmes JM, Repka MX, Pediatric Eye Disease Investigator Group. Recent advances in the treatment of amblyopia. Pediatrics 2004;133(6):1800-2 (Published).
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16. Cotter SA, Chu RH, Chandler DL, et al. Reliability of the Electronic Early Treatment Diabetic Retinopathy Study testing protocol in children 7 to < 13 years old. Am J Ophthalmol 2003;136(4):655-61 (Published).
(Manuscript) | View Publication

17. Repka MX, Pediatric Eye Disease Investigator Group. Moderate amblyopia in children less than seven years of age: experience of the amblyopia treatment study 1. In: de Faber J-T, ed. 9th Meeting of the International Strabismological Association. Sydney, Australia: Swets & Zeitlinger Publishers, 2003;163-6. (Published).
(Manuscript (Non-Peer Reviewed))

18. Beck, RW. Clinical research in pediatric ophthalmology: the Pediatric Eye Disease Investigator Group. Curr Opin Ophthalmol 2002;13(5):337-40 (Published).
(Manuscript (Non-Peer Reviewed)) | View Publication

19. Moke PS, Turpin AH, Beck RW, et al. Computerized method of visual acuity testing: adaption of the amblyopia treatment study visual acuity testing protocol. Am J Ophthalmol 2001;132(6):903-9 (Published).
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20. Holmes JM, Beck RW, Repka MX, et al. The amblyopia treatment visual acuity testing protocol. Arch Ophthalmol 2001;119(9):1345-53 (Published).
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21. Cole SR, Beck RW, Moke PS, et al. The amblyopia treatment index. J AAPOS 2001;5(4):250-4 (Published).
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22. Holmes JM, Beck RW, Kip KE, et al. Predictors of nonrecovery in acute traumatic sixth nerve palsy and paresis. Ophthalmology 2001;108(8):1457-60 (Published).
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23. Holmes JM, Beck RW, Kip KE, et al. Botulinum toxin treatment versus conservative management in acute traumatic sixth nerve palsy or paresis. J AAPOS 2000;4(3):145-9 (Published).
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24. Holmes JM, Leske DA, Droste PJ, Beck RW, Pediatric Eye Disease Investigator Group. A multi-center prospective study of traumatic sixth nerve palsy. In: Lennerstrand G, ed. Advances in Strabismology: Proceedings of the VIII International Strabismus Association. Buren, Netherlands: Aeolus Press, 1999;127-30 (Published).
(Manuscript (Non-Peer Reviewed))

25. Beck RW. The Pediatric Eye Disease Investigator Group. J AAPOS 1998;2(5):255-6 (Published).
(Manuscript (Non-Peer Reviewed)) | View Publication

Protocol - A Randomized Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia

1. Pediatric Eye Disease Investigator Group. A randomized trial of prescribed patching regimens for treatment of severe amblyopia in children. Ophthalmology 2003;110(11):2075-87 (Published).
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Protocol - A Randomized Trial Comparing Part-time Versus Minimal-time Patching for Moderate Amblyopia

1. Pediatric Eye Disease Investigator Group. A randomized trial of patching regimens for treatment of moderate amblyopia in children. Arch Ophthalmol 2003;121(5):603-11 (Published).
(Manuscript) | View Publication

Protocol - Amblyopia Treatment Study 1

1. Repka MX, Kraker RT, Beck RW, et al. Contrast sensitivity following amblyopia treatment in children. Arch Ophthalmol 2009;127(9):1225-7 (Published).
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2. Repka MX, Kraker RT, Beck RW, et al. Monocular oral reading performance after amblyopia treatment in children. Am J Ophthalmol 2008;146(6):942-7 (Published).
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3. Pediatric Eye Disease Investigator Group. A randomized trial of atropine vs patching for treatment of moderate amblyopia: follow-up at age 10 years. Arch Ophthalmol 2008;126(8):1039-44 (Published).
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4. Repka MX, Melia M, Eibschitz-Tsimhoni M, et al. The effect on refractive error of unilateral atropine as compared with patching for the treatment of amblyopia. J AAPOS 2007;11(3):300-2 (Published).
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5. Repka MX, Holmes JM, Melia BM, et al. The effect of amblyopia therapy on ocular alignment. J AAPOS 2005;9(6):542-5 (Published).
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6. Pediatric Eye Disease Investigator Group. Two-year follow-up of a 6-month randomized trial of atropine vs patching for treatment of moderate amblyopia in children. Arch Ophthalmol 2005;123(2):149-57 (Published).
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7. Pediatric Eye Disease Investigator Group. Impact of patching and atropine treatment on the child and family in the amblyopia treatment study. Arch Ophthalmol 2003;121(11):1625-32 (Published).
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8. Pediatric Eye Disease Investigator Group. The course of moderate amblyopia treated with atropine in children: experience of the amblyopia treatment study. Am J Ophthalmol 2003;136(4):630-9 (Published).
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9. Pediatric Eye Disease Investigator Group. The course of moderate amblyopia treated with patching in children: experience of the amblyopia treatment study. Am J Ophthalmol 2003;136(4):620-9 (Published).
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10. Pediatric Eye Disease Investigator Group. A comparison of atropine and patching treatments for moderate amblyopia by patient age, cause of amblyopia, depth of amblyopia, and other factors. Ophthalmology 2003;110(8):1632-7; discussion 1637-8 (Published).
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11. Pediatric Eye Disease Investigator Group. A randomized trial of atropine vs. patching for treatment of moderate amblyopia in children. Arch Ophthalmol 2002;120(3):268-78 (Published).
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12. Pediatric Eye Disease Investigator Group. The clinical profile of moderate amblyopia in children younger than 7 years. Arch Ophthalmol 2002;120(3):281-7 (Published).
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Protocol - Amblyopia Treatment Study 2C

1. Holmes JM, Melia M, Bradfield YS, et al. Factors associated with recurrence of amblyopia on cessation of patching. Ophthalmology 2007;114(8):1427-32 (Published).
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2. Pediatric Eye Disease Investigator Group. Risk of amblyopia recurrence after cessation of treatment. J AAPOS 2004;8(5):420-8 (Published).
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Protocol - Amblyopia Treatment Study 3

1. Pediatric Eye Disease Investigator Group. Stability of visual acuity improvement following discontinuation of amblyopia treatment in children aged 7 to 12 years. Arch Ophthalmol 2007;125(5):655-9 (Published).
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2. Pediatric Eye Disease Investigator Group. Randomized trial of treatment of amblyopia in children aged 7 to 17 years. Arch Ophthalmol 2005;123(4):437-47 (Published).
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3. Pediatric Eye Disease Investigator Group. A prospective, pilot study of treatment of amblyopia in children 10 to < 18 years old. Am J Ophthalmol 2004;137(3):581-3 (Published).
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Protocol - Amblyopia Treatment Study 4

1. Christoff A, Repka MX, Kaminski B, Holmes JM, on behalf of the Pediatric Eye Disease Investigator Group. Distance versus Near Visual Acuity in Amblyopia. J AAPOS 2011;15(4):342-4. (Published).
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2. Pediatric Eye Disease Investigator Group. A randomized trial of atropine regimens for treatment of moderate amblyopia in children. Ophthalmology 2004;111(11):2076-85 (Published).
(Manuscript) | View Publication

Protocol - Amblyopia Treatment Study 5

1. Pediatric Eye Disease Investigator Group. Treatment of strabismic amblyopia with refractive correction. Am J Ophthalmol 2007;143(6):1060-3 (Published).
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2. Pediatric Eye Disease Investigator Group. A randomized trial to evaluate 2 hours of daily patching for strabismic and anisometropic amblyopia in children. Ophthalmology 2006;113(6):904-12 (Published).
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3. Pediatric Eye Disease Investigator Group. Treatment of anisometropic amblyopia in children with refractive correction. Ophthalmology 2006;113(6):895-903 (Published).
(Manuscript) | View Publication

Protocol - Amblyopia Treatment Study 6

1. Pediatric Eye Disease Investigator Group. A randomized trial of near versus distance activities while patching for amblyopia in children aged 3 to less than 7 years. Ophthalmology 2008;115(11):2071-8 (Published).
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2. Pediatric Eye Disease Investigator Group. A randomized pilot study of near activities versus non-near activities during patching therapy for amblyopia. J AAPOS 2005;9(2):129-36 (Published).
(Manuscript) | View Publication

Protocol - Amblyopia Treatment Study 7

1. Pediatric Eye Disease Investigator Group. Treatment of bilateral refractive amblyopia in children three to less than 10 years of age. Am J Ophthalmol 2007;144(4):487-96 (Published).
(Manuscript) | View Publication

Protocol - Amblyopia Treatment Study 8

1. Repka MX, Kraker RT, Beck RW, et al. Treatment of severe amblyopia with atropine: results from two randomized clinical trials. J AAPOS 2009;13(3):258-63 (Published).
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2. Pediatric Eye Disease Investigator Group. Pharmacologic plus optical penalization treatment for amblyopia: results of a randomized trial. Arch Ophthalmol 2009;127(1):22-30 (Published).
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Protocol - Amblyopia Treatment Study 9

1. Felius J, Chandler DL, Holmes JM, et al. Pediatric Eye Disease Investigator Group. Evaluating the Burden of Amblyopia Treatment from the Parent and Child’s Perspective. J AAPOS. 2010; 14(5):389-95. (Published).
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2. Repka MX, Kraker RT, Tamkins SM, et al. Retinal nerve fiber layer thickness in amblyopic eyes. Am J Ophthalmol 2009;148(1):143-7 (Published).
(Manuscript) | View Publication

3. Repka MX, Kraker RT, Beck RW, et al. Treatment of severe amblyopia with atropine: results from two randomized clinical trials. J AAPOS 2009;13(3):258-63 (Published).
(Manuscript) | View Publication

4. Pediatric Eye Disease Investigator Group. Patching vs atropine to treat amblyopia in children aged 7 to 12 years: a randomized trial. Arch Ophthalmol 2008;126(12):1634-42 (Published).
(Manuscript) | View Publication

Protocol - Bangerter Filter Treatment Study

1. Rutstein RP, Foster NC, Cotter SA, et al., Pediatric Eye Disease Investigator Group. Visual acuity through Bangerter filters in nonamblyopic eyes. J AAPOS. 15(2):131-4. Epub 2011 Mar 21. (Published).
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2. Pediatric Eye Disease Investigator Group. A randomized trial comparing Bangerter filters and patching for the treatment of moderate amblyopia in children. Ophthalmology. 2010 May;117(5):998-1004.e6. Epub 2010 Feb 16. (Published).
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Protocol - Central Corneal Thickness Study

1. Pediatric Eye Disease Investigator Group. Central Corneal Thickness in Children. Arch Ophthalmol. 2011;129(9):1132-8. (Published).
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2. Bradfield YB, Kaminski BM, Repka MX, Melia M, et al. on behalf of the Pediatric Eye Disease Investigator Group.. Comparison of Tonopen and Goldmann Applanation Tonometers for Measurement of Intraocular Pressure in Healthy Children. J AAPOS (Accepted).
(Manuscript)

Protocol - Congenital Esotropia Observation Study

1. Pediatric Eye Disease Investigator Group. Spontaneous resolution of early-onset esotropia: experience of the Congenital Esotropia Observational Study. Am J Ophthalmol 2002;133(1):109-18 (Published).
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2. Pediatric Eye Disease Investigator Group. The clinical spectrum of early-onset esotropia: experience of the Congenital Esotropia Observational Study. Am J Ophthalmol 2002;133(1):102-8 (Published).
(Manuscript) | View Publication

3. Birch E, Stager D, Wright K, Beck R, Pediatric Eye Disease Investigator Group. The natural history of infantile esotropia during the first six months of life. J AAPOS 1998;2(6):325-8; discussion 329 (Published).
(Manuscript) | View Publication

Protocol - Correction of Myopia Evaluation Trial 2

1. Correction of Myopia Evaluation Trial 2 Study Group for the Pediatric Eye Disease Investigator Group. Progressive Addition Lenses versus Single Vision Lenses for Slowing Progression of Myopia in Children with High Accommodative Lag and Near Esophoria. Invest Ophthalmol Vis Sci. 2011 Apr 25;52(5):2749-57. Print 2011 May. (Published).
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2. Correction of Myopia Evaluation Trial 2 Study Group. Accommodative lag by autorefraction and two dynamic retinoscopy methods. Optom Vis Sci 2009;86(3):233-43 (Published).
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Protocol - Esotropia Treatment Study 1

1. Melia BM, Holmes JM, Chandler DL, Christiansen SP. Classifying angle stability and instability in childhood esotropia. Arch Ophthalmol;128(12):1555-60 (Published).
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2. Pediatric Eye Disease Investigator Group. The relationship between preoperative alignment stability and postoperative motor outcomes in children with esotropia. J AAPOS 2009;13(4):335-8 (Published).
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3. Pediatric Eye Disease Investigator Group. Interobserver reliability of the Prism and Alternate Cover Test in children with esotropia. Arch Ophthalmol 2009;127(1):59-65 (Published).
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4. Pediatric Eye Disease Investigator Group. Instability of ocular alignment in childhood esotropia. Ophthalmology 2008;115(12):2266–74 (Published).
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Protocol - Levodopa for Amblyopia Pilot

1. Repka MX, Kraker RT, Beck RW, et al. Pilot study of levodopa dose as treatment for residual amblyopia in children aged 8 years to younger than 18 years. Arch Ophthalmol. 2010 Sep;128(9):1215-7. (Published).
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Protocol - Long Term Follow Up of Amblyopia Treatment (ATS1 Extension Study)

1. Kulp MT, Foster NC, Holmes JM, Kraker RT, Melia M, Repka MX, Tien DR, on behalf of the Pediatric Eye Disease Investigator Group.. The Change in Refractive Error in Children <10 years with Amblyopia. Am J Ophthalmol (Accepted).
(Manuscript)

Protocol - Nasolacrimal Duct Obstruction 1

1. Pediatric Eye Disease Investigator Group. Primary treatment of nasolacrimal duct obstruction with balloon catheter dilation in children younger than 4 years of age. J AAPOS 2008;12(5):451-5 (Published).
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2. Pediatric Eye Disease Investigator Group. Primary treatment of nasolacrimal duct obstruction with nasolacrimal duct intubation in children younger than 4 years of age. J AAPOS 2008;12(5):445-50 (Published).
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3. Pediatric Eye Disease Investigator Group. Primary treatment of nasolacrimal duct obstruction with probing in children younger than 4 years. Ophthalmology 2008;115(3):577-84 (Published).
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Protocol - Nasolacrimal Duct Obstruction 2

1. Pediatric Eye Disease Investigator Group. Repeat probing for treatment of persistent nasolacrimal duct obstruction. J AAPOS 2009;13(3):306-7 (Published).
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2. Pediatric Eye Disease Investigator Group. Balloon catheter dilation and nasolacrimal duct intubation for treatment of nasolacrimal duct obstruction after failed probing. Arch Ophthalmol 2009;127(5):633-9 (Published).
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Protocol - Nasolacrimal Duct Obstruction Study 3

1. Pediatric Eye Disease Investigator Group. Resolution of Congenital Nasolacrimal Duct Obstruction with Nonsurgical Management. Arch Ophthalmol (Accepted).
(Manuscript)

2. Writing Committee for the Pediatric Eye Disease Investigator Group. A Randomized Trial Comparing the Cost-Effectiveness of Two Approaches for Treating Unilateral Nasolacrimal Duct Obstruction. Arch Ophthalmol (Submitted for Publication).
(Manuscript)

Protocol - Residual Amblyopia Treatment Study

1. Pediatric Eye Disease Investigator Group. A Randomized Trial to Evaluate Combined Patching and Atropine for Residual Amblyopia. Arch Ophthalmol 2011;129(7):960-2 (Published).
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Protocol - Spectacles for Strabismic Amblyopia

1. Pediatric Eye Disease Investigator Group. Optical Treatment of Strabismic and Combined Strabismic-Anisometropic Amblyopia. Ophthalmology 2011;119(1):150-8. Epub Sep 29. (Published).
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