Pediatric Eye Disease Investigator Group (PEDIG)

Protocol: CCTS - A Prospective Study of Central Corneal Thickness in Children Less than 18 Years Old
Status: Closed
Start Date: 06/02/2008
End Date: 10/13/2009
Clinical Trial ID: N/A
Public Dataset:  Download


A Prospective Study of Central Corneal Thickness in Children Less than 18 Years Old

Protocol

Objectives:
  • Primary objective:
    To determine the distribution of CCT in a normal population of children aged 0 to <18 years and whether this distribution varies within race/ethnicity subpopulations and age groups.
     
  • Secondary objectives:
    The determination of the age at which adult CCT is reached
    The determination of other possible clinical correlates of CCT, including cycloplegic refractive error determined by retinoscopy and IOP
    The comparison of IOP measurements with the GAT and Tonopen instruments in children aged 8 to <18 years and handheld GAT and Tonopen instruments in children 0 to 8 years while under anesthesia.

Published Manuscripts:

  1. Pediatric Eye Disease Investigator Group. "Central corneal thickness in children." Arch Ophthalmol. 2011;129(9):1132-8. PMID: 21911662
  2. Bradfield YS, Kaminski BM, Repka MX, Melia M, for the Pediatric Eye Disease Investigator Group. Comparison of Tono-Pen and Goldmann applanation tonometers for measurement of intraocular pressure in healthy children. J AAPOS. 2012;16(3):242-8. 22459105
  3. Weise KK, Kaminski BM, Melia M, et al. Intraobserver reliability of contact pachymetry in children. J AAPOS. 2013;17(2):144-148.

 



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