Pediatric Eye Disease Investigator Group (PEDIG)

Protocol: ATS11 - A Randomized Trial to Evaluate Combined Patching-Atropine Treatment for Residual Amblyopia
Status: Closed
Start Date: 01/01/2007
End Date: 06/02/2009
Clinical Trial ID: NCT00506675
Public Dataset:  Download

A Randomized Trial to Evaluate Combined Patching-Atropine for Residual Amblyopia


This study is designed to evaluate the effectiveness of treatment of residual amblyopia in children ages 3 to <10 years with visual acuity of 20/32 to 20/63 in the amblyopic eye. The study is a randomized clinical trial comparing intensive treatment (42 hours daily patching plus daily atropine) with a control group that will have rapid weaning of existing treatment followed by spectacle correction only (if needed). The primary objective is to determine if intensive treatment will improve visual acuity in patients with residual amblyopia.



  1. Pediatric Eye Disease Investigator Group. Randomized trial to evaluate combined patching and atropine for residual amblyopia. Arch Ophthalmol 2011;129(7):960-2.




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